Sequence analysis, tissue distribution, and expression of rat cathepsin S.
نویسندگان
چکیده
منابع مشابه
Sequence analysis, tissue distribution, and expression of rat cathepsin S.
Cysteine proteases are involved in many diverse cellular processes ranging from processing of precursor proteins to intracellular degradation. In an effort to identify novel cysteine proteases, we used the polymerase chain reaction and primers directed against the catalytic sites of previously cloned cysteine proteases. From rat brain mRNA, a 600-base pair band was amplified; cloning and partia...
متن کاملHuman cathepsin S: chromosomal localization, gene structure, and tissue distribution.
The human lysosomal cysteine proteinases, cathepsins H, L, and B, have been mapped to chromosomes 15, 9, and 8, respectively, and the genomic structures of cathepsins L and B have been determined. We report here the chromosomal localization and partial gene structure for a recently sequenced human cysteine proteinase, cathepsin S. A 20-kilobase pair genomic clone of the human cathepsin S gene w...
متن کاملCloning, sequence and expression of rat cathepsin D.
Cathepsin D is a member of the family of aspartic proteases and is thought to play a role in the lysosomal-mediated degradation of proteins (1). We have isolated the cDNA for rat cathepsin D from a pituitary cDNA library, screened using oligonucleotide probes synthesized to the conserved active site regions of aspartic proteases (Figure 1). The cDNA contains an open reading frame which encodes ...
متن کاملEffects of Endurance Training on the Expression of Cathepsin B (CTSB) and Cathepsin L (CTSL) genes in the Adipose Tissue of Mice with a High-Fat Diet
Introduction: In high-fat diet-induced obesity, the levels of cathepsin L (CTSL) and cathepsin B (CTSB) increase in adipocytes, resulting in insulin resistance in the adipose tissue. In this study, the preventive effect of endurance training on the gene expression of CTSL and CTSB was investigated in the adipose tissue of mice with a high-fat diet. Materials and Methods: Twenty-one male mice (a...
متن کاملPrimary root growth, tissue expression and co-expression analysis of a receptor kinase mutant in Arabidopsis
There is no functional annotation for the majority of the several hundreds of receptor-like kinases in plants. A direct way of inferring the function of these proteins is to study the phenotype that results from loss of function mutants such as T-DNA mutant lines. In this research a function (phenotype) to At2g37050 gene that encodes a receptor like kinase in Arabidopsis T-DNA line was...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1992
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)35713-2